Research

Michelson Diagnostics' optical coherence tomography technology is now being used by several research institutions.

The company is pleased to publish the papers and conference and symposia talks delivered of major significance below.

Papers in peer reviewed journals 

Jerjes, W., et al "Oral leukoplakia and erythroplakia subjected to optical coherence tomography: preliminary results" British Journal of Oral & Maxillofacial Surgery Volume 46, Issue 7, October 2008, Page e7

Tomlins PH, Woolliams P, Hart C, Beaumont A, Tedaldi M."Optical coherence refractometry" Opt Lett. 2008 Oct 1;33(19):2272-4 See abstract

Marcauteanu, C et al "Noninvasive Alternative Techniques for the Early Detection of Occlusal Overload" European Cells and Materials Vol. 16. Suppl. 5, 2008 (page 5) See paper

Hamdoon, Z et al "Immediate ex vivo optical coherence tomography of suspicious oral lesions" British Journal of Oral and Maxillofacial Surgery Volume 47, Issue 7, October 2009, Pages e51-e52 See abstract

Jerjes, W et al "In vitro examination of suspicious oral lesions using optical coherence tomography" British Journal of Oral and Maxillofacial Surgery Volume 48, Issue 1, January 2010, Pages 18-25 See abstract

Dr Beau Standish et al "In-vivo endoscopic multi-beam optical coherence tomography"  Phys. Med. Biol. 55 (2010) 615-622 See article

Peter D. Woolliams, Robert A. Ferguson, Christian Hart, Alex Grimwood, and Peter H. Tomlins, "Spatially deconvolved optical coherence tomography," Appl. Opt. 49, 2014-2021 (2010) See abstract

Donnelly, R F et al "Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique" Journal of Pharmaceutical Research 19 May 2010 DOI 10.1007/s11095-010-0169-8 See abstract

Smith LE, Bonesi M, Smallwood R, Matcher SJ, Macneil S."Using swept-source optical coherence tomography to monitor the formation of neo-epidermis in tissue-engineered skin" J Tissue Eng Regen Med. 2010 Jul 5 See abstract

Donnelly, R F et al "Optical coherence tomography is a valuable tool in the study of the effects of microneedle geometry on skin penetration characteristics and in-skin dissolution" Journal of Controlled Release (2010) [IN PRESS] See abstract

Alex Grimwood et al "Elastographic contrast generation in optical coherence tomography from a localized shear stress" 2010 Phys. Med. Biol. 55 5515 doi: 10.1088/0031-9155/55/18/016 See abstract

Conference papers

J. Holmes, S. Hattersley, N. Stone, et al (2008) "Multichannel Fourier domain OCT system with superior lateral resolution for biomedical applications" Ed. J. A. Izatt, et al. Vol. 6847, pp. 68470O. Presented at Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, SPIE

Holmes, J. (2008) "Theory and applications of Multi-Beam OCT" Eds. Podoleanu, A. Vol. 7139, pp. 713908-713907. Presented at 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, SPIE, Canterbury, United Kingdom  See abstract

Mohammad R. N. Avanaki and Ali Hojjat "Speckle reduction with attenuation compensation for Skin OCT images enhancement" Presented at Medical Image Understanding & Analysis 15 July 2009

Florian Bazant-Hegemark, Gordon McKenzie, Simon Hattersley, Jon Holmes. "Decorrelation of Dynamic Speckle as Endogenous Contrast for Vascular Flow in Video-Rate Multi-Beam Resolution Swept-Source Optical Coherence Tomography (OCT)" Presented at MICCAI Workshop on Optical Tissue Image analysis in Microscopy, Histopathology and Endoscopy Imperial College London September 24th 2009 See paper

K.Konig et al "Clinical optical coherence tomography combined with multiphoton tomography for evaluation of several skin disorders" Ed. J. A. Izatt, et al. Vol. 7554, 75542I (2010).  Poster presented at Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, SPIE See abstract

F. Bazant-Hegemark et al "Multi-beam resolution video-rate swept-source optical coherence tomography (OCT) provides endogenous contrast for in vivo blood flow independent of flow direction" Ed. J. A. Izatt, et al.  Vol. 7554, 75542Z (2010). Poster presented at Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, SPIE See abstract

D. Cunha, T. Richardson, N. Sheth, G. Orchard, A. Coleman and R. Mallipeddi "Comparison of ex vivo optical coherence tomography with conventional frozen-section histology for visualizing basal cell carcinoma during Mohs micrographic surgery" British Journal of Dermatology 2010 163 (Suppl. 1), pp101–117 See paper

Articles

Bazant-Hegemark F, Stone N, McKenzie G and Holmes J. "Optical Coherence Tomography aids cancer detection" Biophotonics International, November 2007; 46 – 7 Download pdf 

Jon Holmes. "OCT technology development: Where are we now?" J. Biophoton. 1–9 (2009) / DOI 10.1002/jbio.200910014 See article

Florian Bazant-Hegemark, Daniel Woods. "Optische Kohärenztomographie – vom Forschungsgegenstand zum Forschungswerkzeug” BioPhotonik, März 2010, pp24-26 See article

Jon Holmes. "In vivo real-time optical coherence tomography imaging of Drosophila for cardiovascular research" Nature Methods, October 2009, Volume 6 No 10 p iii-iv See article

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